InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Smarcal1

Summary

InnateDB Protein

IDBP-715161.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Smarcal1

Protein Name

Synonyms

6030401P21Rik; AI851716; Mharp;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000137833

InnateDB Gene

IDBG-165790 (Smarcal1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0004386	helicase activity
GO:0005524	ATP binding
GO:0008094	DNA-dependent ATPase activity
GO:0036310	annealing helicase activity

Biological Process

GO:0000733	DNA strand renaturation
GO:0006200	ATP catabolic process
GO:0006259	DNA metabolic process
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006974	cellular response to DNA damage stimulus
GO:0016568	chromatin modification
GO:0031297	replication fork processing

Cellular Component

GO:0005634	nucleus
GO:0005662	DNA replication factor A complex
GO:0035861	site of double-strand break

Protein Structure and Domains

PDB ID

MGI:1859183

InterPro

IPR000330 SNF2-related
IPR001650 Helicase, C-terminal
IPR010003 HARP domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00176
PF00271
PF07443

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BJL0