Version 5.4
| Homo sapiens Protein: POU5F2 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-717437.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | POU5F2 | ||||||||
| Protein Name | |||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000464890 | ||||||||
| InnateDB Gene | IDBG-407445 (POU5F2) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Transcription factor that binds preferentially to the octamer motif (5'-ATGTTAAT-3'). May exert a regulatory function in meiotic events that are required for terminal differentiation of male germ cell (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Nucleus {ECO:0000255PROSITE- ProRule:PRU00108, ECO:0000255PROSITE-ProRule:PRU00530}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in skeletal and cardiac muscles, brain, heart and lung. Little or no detectable expression found in pancreas, kidney, liver or placenta. {ECO:0000269PubMed:7908264}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000327
POU-specific IPR001356 Homeobox domain IPR009057 Homeodomain-like IPR010982 Lambda repressor-like, DNA-binding domain IPR013847 POU domain |
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| PFAM |
PF00157
PF00046 PF13413 |
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| PRINTS |
PR00028
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| PIRSF | |||||||||
| SMART |
SM00352
SM00389 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8N7G0 | ||||||||
| PhosphoSite | PhosphoSite-Q8N7G0 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 134187 | ||||||||
| UniGene | |||||||||
| RefSeq | NP_694948 | ||||||||
| HUGO | HGNC:26367 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS59489 | ||||||||
| HPRD | 08695 | ||||||||
| IMGT | |||||||||
| EMBL | AK098546 BC029532 BX641019 Z21965 | ||||||||
| GenPept | AAH29532 BAC05328 CAA79976 CAE46012 | ||||||||