InnateDB Protein
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IDBP-71754.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TRO
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Protein Name
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trophinin
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Synonyms
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MAGE-d3; MAGED3;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000364162
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InnateDB Gene
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IDBG-71746 (TRO)
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Protein Structure
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Function |
Could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Directly responsible for homophilic cell adhesion.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Strong expression at implantation sites. Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi. Also found in macrophages.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
8
[view]
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Protein-Protein |
8
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002190
MAGE protein
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PFAM |
PF01454
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q12816
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PhosphoSite |
PhosphoSite-Q12816
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TrEMBL |
E7ERU6
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UniProt Splice Variant |
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Entrez Gene |
7216
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UniGene |
Hs.743294
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RefSeq |
NP_808224
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HUGO |
HGNC:12326
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OMIM |
300132
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CCDS |
CCDS43958
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HPRD |
02134
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IMGT |
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EMBL |
AB029037
AK027489
AL049732
CH471154
U04811
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GenPept |
AAA79334
BAA83066
BAB55149
CAB86651
CAM26850
EAW93200
EAW93201
EAW93205
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