InnateDB Protein
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IDBP-71776.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FYTTD1
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Protein Name
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forty-two-three domain containing 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000241502
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InnateDB Gene
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IDBG-71774 (FYTTD1)
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Protein Structure
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Function |
Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4. {ECO:0000269PubMed:19836239}.
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Subcellular Localization |
Nucleus, nucleoplasm {ECO:0000269PubMed:19836239}. Nucleus speckle {ECO:0000269PubMed:19836239}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
25
[view]
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Protein-Protein |
25
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR009782
Protein of unknown function DUF1346
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PFAM |
PF07078
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q96QD9
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PhosphoSite |
PhosphoSite-Q96QD9
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TrEMBL |
H9KVC6
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UniProt Splice Variant |
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Entrez Gene |
84248
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UniGene |
Hs.602541
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RefSeq |
NP_115664
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HUGO |
HGNC:25407
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OMIM |
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CCDS |
CCDS3329
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HPRD |
10909
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IMGT |
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EMBL |
AC024560
AC055764
AJ344094
AK027672
AK296283
AK302546
AK303462
AK315019
AK316308
AL136558
BC035006
BC039734
CH471252
CR533502
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GenPept |
AAH35006
AAH39734
BAB55284
BAG37509
BAH12300
BAH13737
BAH13966
BAH14679
CAB66493
CAC51432
CAG38533
EAW92240
EAW92241
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