Version 5.4
Mus musculus Protein: Gpr124
Summary
InnateDB Protein IDBP-717799.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpr124
Protein Name
Synonyms 8430414O08Rik; 9530074E10Rik; mKIAA1531; Tem5;
Species Mus musculus
Ensembl Protein ENSMUSP00000136277
InnateDB Gene IDBG-145588 (Gpr124)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0005515 protein binding
Biological Process
GO:0001525 angiogenesis
GO:0002040 sprouting angiogenesis
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0010595 positive regulation of endothelial cell migration
GO:0090210 regulation of establishment of blood-brain barrier
GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1925810
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
IPR000832 GPCR, family 2, secretin-like
IPR001611 Leucine-rich repeat
IPR001879 GPCR, family 2, extracellular hormone receptor domain
IPR003591 Leucine-rich repeat, typical subtype
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR017981 GPCR, family 2-like
PFAM PF01463
PF00002
PF00560
PF13504
PF13855
PF02793
PRINTS PR00249
PIRSF
SMART SM00082
SM00008
SM00369
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL J3QMG7
UniProt Splice Variant
Entrez Gene 78560
UniGene Mm.87046
RefSeq
MGI ID
MGI Symbol Gpr124
OMIM
CCDS
HPRD
IMGT
EMBL AC115820 AC119917
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca