InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Meis1

Summary

InnateDB Protein

IDBP-718082.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Meis1

Protein Name

Synonyms

C530044H18Rik; Evi8;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000135726

InnateDB Gene

IDBG-152330 (Meis1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Experimentally validated
Total	29 [view]
Protein-Protein	25 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0001525	angiogenesis
GO:0002089	lens morphogenesis in camera-type eye
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0030097	hemopoiesis
GO:0035855	megakaryocyte development
GO:0045665	negative regulation of neuron differentiation
GO:0048514	blood vessel morphogenesis
GO:0060216	definitive hemopoiesis

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex

Protein Structure and Domains

PDB ID

MGI:104717

InterPro

IPR001356 Homeobox domain
IPR008422 Homeobox KN domain
IPR009057 Homeodomain-like

PFAM

PF00046
PF05920

PRINTS

PIRSF

SMART

SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

H3BLB6

UniProt Splice Variant

Entrez Gene

17268

UniGene

Mm.445192

RefSeq

XP_006514623

MGI ID

MGI Symbol

Meis1

OMIM

CCDS

HPRD

IMGT

EMBL

AL603984 AL645570

GenPept