InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CFTR

Summary

InnateDB Protein

IDBP-718373.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CFTR

Protein Name

Synonyms

ABC35; ABCC7; CF; CFTR/MRP; dJ760C5.1; MRP7; TNR-CFTR;

Species

Homo sapiens

Ensembl Protein

ENSP00000470177

InnateDB Gene

IDBG-37713 (CFTR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 316 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	316 [view]
Protein-Protein	303 [view]
Protein-DNA	11 [view]
Protein-RNA	2 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0016887	ATPase activity

Biological Process

GO:0045087

innate immune response (InnateDB)

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR003439 ABC transporter-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00005

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q6KEA5

UniProt Splice Variant

Entrez Gene

1080

UniGene

Hs.661104

RefSeq

HUGO

HGNC:1884

OMIM

602421

CCDS

HPRD

03883

IMGT

EMBL

AJ575041 AJ575042 AJ575043 AJ575044 AJ575045 AJ575046 AJ575047 AJ575048 AJ575049 AJ575050

GenPept

CAE00755 CAE00756 CAE00757 CAE00758 CAE00759 CAE00760 CAE00761 CAE00762 CAE00763 CAE00764