InnateDB Protein
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IDBP-718391.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Lsm10
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Protein Name
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000136585
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InnateDB Gene
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IDBG-187817 (Lsm10)
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Protein Structure
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Function |
Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing (By similarity). Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed (By similarity). Required for cell cycle progression from G1 to S phases (By similarity). Binds specifically to U7 snRNA (By similarity). Binds specifically to U7 snRNA (By similarity). Binds to the downstream cleavage product (DCP) of histone pre-mRNA. {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
8 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2151045
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InterPro |
IPR001163
Ribonucleoprotein LSM domain
IPR006649
Ribonucleoprotein LSM domain, eukaryotic/archaea-type
IPR010920
Like-Sm (LSM) domain
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PFAM |
PF01423
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PRINTS |
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PIRSF |
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SMART |
SM00651
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TIGRFAMs |
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Modification |
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SwissProt |
Q8QZX5
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PhosphoSite |
PhosphoSite-Q8QZX5
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TrEMBL |
Q3UPL7
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UniProt Splice Variant |
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Entrez Gene |
116748
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UniGene |
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RefSeq |
NP_001156738
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MGI ID |
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MGI Symbol |
Lsm10
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OMIM |
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CCDS |
CCDS18642
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HPRD |
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IMGT |
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EMBL |
AK143443
AL627101
BC024543
BC026476
CH466552
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GenPept |
AAH24543
AAH26476
BAE25378
EDL30310
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