Version 5.4
Mus musculus Protein: Lhx2
Summary
InnateDB Protein IDBP-718752.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lhx2
Protein Name
Synonyms ap; apterous; Lh-2; LH2A; Lim2;
Species Mus musculus
Ensembl Protein ENSMUSP00000135402
InnateDB Gene IDBG-166617 (Lhx2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001076 RNA polymerase II transcription factor binding transcription factor activity
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001843 neural tube closure
GO:0006366 transcription from RNA polymerase II promoter
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0007420 brain development
GO:0007498 mesoderm development
GO:0009953 dorsal/ventral pattern formation
GO:0021537 telencephalon development
GO:0021772 olfactory bulb development
GO:0021978 telencephalon regionalization
GO:0021987 cerebral cortex development
GO:0022008 neurogenesis
GO:0030182 neuron differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048646 anatomical structure formation involved in morphogenesis
GO:0048675 axon extension
GO:0060041 retina development in camera-type eye
GO:2000678 negative regulation of transcription regulatory region DNA binding
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:96785
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H3BKI3
UniProt Splice Variant
Entrez Gene 16870
UniGene Mm.142856
RefSeq
MGI ID
MGI Symbol Lhx2
OMIM
CCDS
HPRD
IMGT
EMBL AL929186 BX813320
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca