InnateDB Protein
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IDBP-719029.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ccl27b
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Protein Name
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000137284
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InnateDB Gene
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IDBG-709218 (Ccl27b)
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Protein Structure
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Function |
Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10.
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Subcellular Localization |
Isoform 1: Secreted. Nucleus. Note=May also be nuclear when following receptor (CCR10)-mediated internalization.Isoform 2: Nucleus.
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Disease Associations |
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Tissue Specificity |
Isoform 1 is predominantly expressed in placenta and weakly in skin. Isoform 2 is predominantly expressed in testes and brain, weakly in kidney and liver and even lower in heart and muscle. Low expression of both isoforms in other tissues.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1891389
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InterPro |
IPR001811
Chemokine interleukin-8-like domain
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PFAM |
PF00048
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PRINTS |
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PIRSF |
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SMART |
SM00199
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Z1X0
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
102641963
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UniGene |
Mm.483954
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RefSeq |
NP_001254633
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MGI ID |
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MGI Symbol |
Ccl27b
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OMIM |
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CCDS |
CCDS51159
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HPRD |
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IMGT |
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EMBL |
AB013398
AF082392
AF099931
AK005398
AK005520
BC028511
BC107226
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GenPept |
AAD04163
AAD41237
AAH28511
AAI07227
BAA88474
BAB24001
BAB24095
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