Version 5.4
Homo sapiens Protein: ENTHD2
Summary
InnateDB Protein IDBP-72088.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ENTHD2
Protein Name chromosome 17 open reading frame 56
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000300714
InnateDB Gene IDBG-72086 (ENTHD2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm, cytosol {ECO:0000269PubMed:22472443}. Cytoplasmic vesicle {ECO:0000269PubMed:22472443}. Note=Extensively colocalizes with AP-4 in a punctate juxtanuclear pattern, which likely corresponds to trans-Golgi network. Requires a functional AP-4 complex for recruitment to vesicle membrane.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005829 cytosol
GO:0016023 cytoplasmic membrane-bounded vesicle
Protein Structure and Domains
PDB ID
InterPro IPR001026 Epsin domain, N-terminal
IPR008942 ENTH/VHS
PFAM PF01417
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96N21
PhosphoSite PhosphoSite-Q96N21
TrEMBL A0A024R8Q8
UniProt Splice Variant
Entrez Gene 146705
UniGene Hs.733099
RefSeq NP_653280
HUGO HGNC:26458
OMIM
CCDS CCDS11779
HPRD 08103
IMGT
EMBL AK056090 AK127221 AK128728 BC064483 CH471099
GenPept AAH64483 BAB71091 BAC86888 BAC87593 EAW89637 EAW89638

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca