Version 5.4
Homo sapiens Protein: TNFRSF18
Summary
InnateDB Protein IDBP-722082.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNFRSF18
Protein Name
Synonyms AITR; CD357; GITR; GITR-D;
Species Homo sapiens
Ensembl Protein ENSP00000462735
InnateDB Gene IDBG-84584 (TNFRSF18)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR001368 TNFR/NGFR cysteine-rich region
IPR022318 Tumour necrosis factor receptor 18
PFAM PF00020
PRINTS PR01968
PIRSF
SMART SM00208
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL J3KT02
UniProt Splice Variant
Entrez Gene 8784
UniGene Hs.212680
RefSeq
HUGO HGNC:11914
OMIM 603905
CCDS
HPRD 04879
IMGT
EMBL AL162741
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca