Version 5.4
| Mus musculus Protein: Rlbp1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-722291.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Rlbp1 | ||||||||
| Protein Name | |||||||||
| Synonyms | 3110056M11Rik; CRALBP; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000137143 | ||||||||
| InnateDB Gene | IDBG-193754 (Rlbp1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. | ||||||||
| Subcellular Localization | Cytoplasm. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Retina and pineal gland. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:97930 | ||||||||
| InterPro |
IPR001071
Cellular retinaldehyde binding/alpha-tocopherol transport IPR001251 CRAL-TRIO domain IPR011074 CRAL/TRIO, N-terminal domain |
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| PFAM |
PF00650
PF13716 PF03765 |
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| PRINTS |
PR00180
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| PIRSF | |||||||||
| SMART |
SM00516
SM01100 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9Z275 | ||||||||
| PhosphoSite | PhosphoSite-Q9Z275 | ||||||||
| TrEMBL | Q544Y3 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 19771 | ||||||||
| UniGene | Mm.41653 | ||||||||
| RefSeq | NP_001166954 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Rlbp1 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS39990 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF084638 AF084639 AF084640 AF084641 AF084642 AK014227 AK140622 BC016268 CH466543 | ||||||||
| GenPept | AAC99427 AAH16268 BAB29216 BAE24430 EDL07072 EDL07073 | ||||||||