InnateDB Protein
|
IDBP-722842.3
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Meis3
|
Protein Name
|
|
Synonyms
|
AI573393; Mrg2;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000134918
|
InnateDB Gene
|
IDBG-146061 (Meis3)
|
Protein Structure
|
|
Function |
|
Subcellular Localization |
Nucleus {ECO:0000305}.
|
Disease Associations |
|
Tissue Specificity |
Expressed at high levels in the brain. Significant expression also observed in the heart, spleen and lung.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
3
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0001077
|
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
|
GO:0003677
|
DNA binding
|
GO:0003682
|
chromatin binding
|
GO:0003700
|
sequence-specific DNA binding transcription factor activity
|
GO:0043565
|
sequence-specific DNA binding
|
|
Biological Process |
GO:0006355
|
regulation of transcription, DNA-templated
|
GO:0045944
|
positive regulation of transcription from RNA polymerase II promoter
|
GO:0051897
|
positive regulation of protein kinase B signaling
|
GO:2001234
|
negative regulation of apoptotic signaling pathway
|
|
Cellular Component |
|
PDB ID |
MGI:108519
|
InterPro |
IPR001356
Homeobox domain
IPR008422
Homeobox KN domain
IPR009057
Homeodomain-like
|
PFAM |
PF00046
PF05920
|
PRINTS |
|
PIRSF |
|
SMART |
SM00389
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P97368
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
H3BKH0
|
UniProt Splice Variant |
|
Entrez Gene |
17537
|
UniGene |
Mm.360516
|
RefSeq |
NP_001264918
|
MGI ID |
|
MGI Symbol |
Meis3
|
OMIM |
|
CCDS |
CCDS71892
|
HPRD |
|
IMGT |
|
EMBL |
AC156630
BC003762
BC117532
CH466654
U57344
|
GenPept |
AAC52949
AAH03762
AAI17533
EDL42107
|
|
|