Version 5.4
Homo sapiens Protein: SERPINB5
Summary
InnateDB Protein IDBP-725998.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERPINB5
Protein Name
Synonyms maspin; PI5;
Species Homo sapiens
Ensembl Protein ENSP00000467158
InnateDB Gene IDBG-4411 (SERPINB5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 17 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0006928 cellular component movement
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000240 Serpin B9/maspin
IPR023796 Serpin domain
PFAM PF00079
PRINTS PR00676
PIRSF
SMART SM00093
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P36952
PhosphoSite PhosphoSite-P36952
TrEMBL C9JLM5
UniProt Splice Variant
Entrez Gene 5268
UniGene Hs.622094
RefSeq
HUGO HGNC:8949
OMIM 154790
CCDS
HPRD 01111
IMGT
EMBL AC036176 AK312765 BC020713 BX640597 U04313
GenPept AAA18957 AAH20713 BAG35631 CAE45703

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca