Version 5.4
Homo sapiens Protein: PPP1R27
Summary
InnateDB Protein IDBP-72643.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R27
Protein Name protein phosphatase 1, regulatory subunit 27
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000331065
InnateDB Gene IDBG-72641 (PPP1R27)
Protein Structure
UniProt Annotation
Function Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. {ECO:0000269PubMed:19389623}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004864 protein phosphatase inhibitor activity
GO:0005515 protein binding
GO:0019902 phosphatase binding
Biological Process
GO:0010923 negative regulation of phosphatase activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86WC6
PhosphoSite PhosphoSite-Q86WC6
TrEMBL I3L267
UniProt Splice Variant
Entrez Gene 116729
UniGene Hs.454720
RefSeq NP_001007534
HUGO HGNC:16813
OMIM
CCDS CCDS32767
HPRD 17334
IMGT
EMBL AC174470 AF434846 BC093707 BC112094
GenPept AAH93707 AAI12095 AAO67357

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca