Version 5.4
Homo sapiens Protein: SPIN2B
Summary
InnateDB Protein IDBP-72680.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPIN2B
Protein Name spindlin family, member 2B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000335008
InnateDB Gene IDBG-72707 (SPIN2B)
Protein Structure
UniProt Annotation
Function Involved in the regulation of cell cycle progression, this activity is related to the inhibition of apoptosis following the removal of essential growth factors. {ECO:0000269PubMed:12145692}.
Subcellular Localization Nucleus {ECO:0000269PubMed:12145692}.
Disease Associations
Tissue Specificity Detected in all the examined tissues with highest expression in liver, followed by heart, stomach, kidney, skeletal muscle, placenta, and pancreas.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006915 apoptotic process
GO:0007049 cell cycle
GO:0007276 gamete generation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR003671 Spindlin/spermiogenesis-specific protein
PFAM PF02513
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BPZ2
PhosphoSite PhosphoSite-Q9BPZ2
TrEMBL Q5JZB8
UniProt Splice Variant
Entrez Gene 54466
UniGene Hs.740639
RefSeq NP_001006682
HUGO HGNC:33147
OMIM 300621
CCDS CCDS35311
HPRD 18662
IMGT
EMBL AF356353 AL022157 BC000044 BC071974 CH471154
GenPept AAH00044 AAH71974 AAK37566 CAI42600 EAW93238 EAW93239

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca