Version 5.4
Homo sapiens Protein: KCNJ3
Summary
InnateDB Protein IDBP-72683.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNJ3
Protein Name potassium inwardly-rectifying channel, subfamily J, member 3
Synonyms GIRK1; KGA; KIR3.1;
Species Homo sapiens
Ensembl Protein ENSP00000295101
InnateDB Gene IDBG-72681 (KCNJ3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005242 inward rectifier potassium channel activity
GO:0005515 protein binding
GO:0015467 G-protein activated inward rectifier potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0051602 response to electrical stimulus
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0030315 T-tubule
Protein Structure and Domains
PDB ID
InterPro IPR003274 Potassium channel, inwardly rectifying, Kir3.1
IPR014756 Immunoglobulin E-set
IPR016449 Potassium channel, inwardly rectifying, Kir
PFAM PF01007
PRINTS PR01327
PR01320
PIRSF PIRSF005465
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48549
PhosphoSite PhosphoSite-P48549
TrEMBL Q53R59
UniProt Splice Variant
Entrez Gene 3760
UniGene Hs.629939
RefSeq NP_002230
HUGO HGNC:6264
OMIM 601534
CCDS CCDS2200
HPRD 03323
IMGT
EMBL AC061961 AC093633 AC107060 AK293824 BC022495 GU074515 U39196 U50964
GenPept AAB42176 AAB53094 AAH22495 AAX93197 ADB11081 BAG57228

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca