InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BAIAP2L2

Summary

InnateDB Protein

IDBP-7293.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BAIAP2L2

Protein Name

BAI1-associated protein 2-like 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000371085

InnateDB Gene

IDBG-7291 (BAIAP2L2)

Protein Structure

UniProt Annotation

Function

Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity). {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000269PubMed:21743456}; Peripheral membrane protein {ECO:0000269PubMed:21743456}. Cell junction {ECO:0000269PubMed:21743456}. Cytoplasmic vesicle membrane {ECO:0000269PubMed:21743456}. Note=Localizes to RAB13- positive vesicles and to the plasma membrane at intercellular contacts.

Disease Associations

Tissue Specificity

Expressed in the epithelial layer of the intestine (at protein level). {ECO:0000269PubMed:21743456}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005543	phospholipid binding
GO:0008093	cytoskeletal adaptor activity
GO:0017124	SH3 domain binding

Biological Process

GO:0007009	plasma membrane organization
GO:0007165	signal transduction
GO:0032956	regulation of actin cytoskeleton organization
GO:0046847	filopodium assembly
GO:0061024	membrane organization