Version 5.4
Homo sapiens Protein: NDRG3
Summary
InnateDB Protein IDBP-73088.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NDRG3
Protein Name NDRG family member 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000345292
InnateDB Gene IDBG-73084 (NDRG3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitous. Highly expressed in brain. {ECO:0000269PubMed:11352569}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007283 spermatogenesis
GO:0030154 cell differentiation
GO:0030308 negative regulation of cell growth
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000073 Alpha/beta hydrolase fold-1
IPR004142 NDRG
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00561
PF03096
PRINTS PR00111
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UGV2
PhosphoSite PhosphoSite-Q9UGV2
TrEMBL
UniProt Splice Variant
Entrez Gene 57446
UniGene Hs.613722
RefSeq NP_114402
HUGO HGNC:14462
OMIM 605273
CCDS CCDS13285
HPRD 12007
IMGT
EMBL AB044943 AF251054 AF308609 AK023618 AK027665 AL031662 AL132768 BC136489 CH471077
GenPept AAI36490 AAK34944 AAL08807 BAB14620 BAB20067 BAB55277 CAI21399 CAI21461 CAM28251 CAM45843 EAW76109 EAW76112 EAW76114 EAW76115

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca