Version 5.4
Homo sapiens Protein: FRMD3
Summary
InnateDB Protein IDBP-73469.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FRMD3
Protein Name FERM domain containing 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000328615
InnateDB Gene IDBG-73463 (FRMD3)
Protein Structure
UniProt Annotation
Function Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. {ECO:0000269PubMed:17260017}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Ovary-specific. {ECO:0000269PubMed:12601556}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008092 cytoskeletal protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0016021 integral component of membrane
GO:0019898 extrinsic component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2A2Y4
PhosphoSite PhosphoSite-A2A2Y4
TrEMBL
UniProt Splice Variant
Entrez Gene 257019
UniGene Hs.743606
RefSeq NP_001231891
HUGO HGNC:24125
OMIM 607619
CCDS CCDS59131
HPRD 07402
IMGT
EMBL AK094281 AK223597 AK297722 AL137847 AL161786 AL450026 AY137774 BC023560 BC037253 CH471089 EF560742
GenPept AAH23560 AAH37253 AAN52119 ABQ59052 BAC04321 BAD97317 BAG60076 CAH72749 CAH72750 CAI40734 CAI40735 CAI40736 CAM17460 CAM19643 CAM19644 CAM19673 EAW62647 EAW62649 EAW62650 EAW62651

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca