Version 5.4
Homo sapiens Protein: HEXDC
Summary
InnateDB Protein IDBP-73551.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HEXDC
Protein Name hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000337854
InnateDB Gene IDBG-73547 (HEXDC)
Protein Structure
UniProt Annotation
Function Has hexosaminidase activity. {ECO:0000269PubMed:19040401}.
Subcellular Localization Cytoplasm. Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004563 beta-N-acetylhexosaminidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR015883 Glycoside hydrolase family 20, catalytic core
IPR017853 Glycoside hydrolase, superfamily
PFAM PF00728
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WVB3
PhosphoSite PhosphoSite-
TrEMBL J3QLN1
UniProt Splice Variant
Entrez Gene 284004
UniGene Hs.444743
RefSeq NP_775891
HUGO HGNC:26307
OMIM
CCDS CCDS42402
HPRD 08677
IMGT
EMBL AC132938 AK074405 BC018205 BC035561 CH471099 FM204887
GenPept AAH18205 AAH35561 BAB85072 CAR57925 EAW89773

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca