Version 5.4
Homo sapiens Protein: SOGA1
Summary
InnateDB Protein IDBP-73612.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SOGA1
Protein Name KIAA0889
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000237536
InnateDB Gene IDBG-73608 (SOGA1)
Protein Structure
UniProt Annotation
Function Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner. {ECO:0000250}.
Subcellular Localization C-terminal 80 kDa form: Secreted {ECO:0000250}. Note=Secreted in primary hepatocyte-conditioned media. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008286 insulin receptor signaling pathway
GO:0010506 regulation of autophagy
GO:0045721 negative regulation of gluconeogenesis
Cellular Component
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR027881 Protein SOGA
PFAM PF11365
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O94964
PhosphoSite PhosphoSite-O94964
TrEMBL I3L0I1
UniProt Splice Variant
Entrez Gene 140710
UniGene Hs.460807
RefSeq NP_542194
HUGO HGNC:16111
OMIM
CCDS CCDS54459
HPRD 18553
IMGT
EMBL AB020696 AK022023 AK126630 AL079335 AL132768 AL391602 BC113405 BC113433 BK007092
GenPept AAI13406 AAI13434 BAA74912 BAB13954 BAC86621 CAI12788 CAI21460 CAI42289 DAA34786

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca