Version 5.4
Homo sapiens Protein: TMEM25
Summary
InnateDB Protein IDBP-73940.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM25
Protein Name transmembrane protein 25
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000346237
InnateDB Gene IDBG-73934 (TMEM25)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Isoform 1: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.Isoform 4: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.Isoform 2: Secreted {ECO:0000305}.Isoform 3: Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR007110 Immunoglobulin-like domain
IPR013162 CD80-like, immunoglobulin C2-set
PFAM PF08205
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86YD3
PhosphoSite PhosphoSite-Q86YD3
TrEMBL E9PI73
UniProt Splice Variant
Entrez Gene 84866
UniGene Hs.564188
RefSeq NP_001137509
HUGO HGNC:25890
OMIM 613934
CCDS CCDS44745
HPRD 11635
IMGT
EMBL AK027305 AK056325 AK075437 AK292359 AP000941 AY358919 BC042896 BC051841 CH471065 EF445037
GenPept AAH42896 AAH51841 AAQ89278 ACA06084 ACA06085 ACA06086 ACA06087 BAB55029 BAB71151 BAC11620 BAF85048 EAW67388 EAW67389 EAW67390 EAW67393

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca