InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TIMM23B

Summary

InnateDB Protein

IDBP-74140.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TIMM23B

Protein Name

translocase of inner mitochondrial membrane 23 homolog B (yeast)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000363211

InnateDB Gene

IDBG-74138 (TIMM23B)

Protein Structure

UniProt Annotation

Function

May participate in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane. the PAM complex (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity

Biological Process

GO:0006886	intracellular protein transport
GO:0008150	biological_process
GO:0071806	protein transmembrane transport

Cellular Component

GO:0005575	cellular_component
GO:0005744	mitochondrial inner membrane presequence translocase complex
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003397 Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24
IPR005681 Mitochondrial inner membrane translocase complex, subunit Tim23

PFAM

PF02466

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5SRD1

PhosphoSite