Version 5.4
Mus musculus Protein: Ryk
Summary
InnateDB Protein IDBP-741893.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ryk
Protein Name
Synonyms AW536699; ERK-3; Vik;
Species Mus musculus
Ensembl Protein ENSMUSP00000135396
InnateDB Gene IDBG-194079 (Ryk)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 64 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 64 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017147 Wnt-protein binding
GO:0042813 Wnt-activated receptor activity
Biological Process
GO:0007409 axonogenesis
GO:0016055 Wnt signaling pathway
GO:0043410 positive regulation of MAPK cascade
GO:0048705 skeletal system morphogenesis
GO:0048843 negative regulation of axon extension involved in axon guidance
GO:0050919 negative chemotaxis
GO:0071679 commissural neuron axon guidance
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:101766
InterPro IPR003306 WIF domain
PFAM PF02019
PRINTS
PIRSF
SMART SM00469
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q71UK0
UniProt Splice Variant
Entrez Gene 20187
UniGene Mm.404722
RefSeq NP_001271187
MGI ID
MGI Symbol Ryk
OMIM
CCDS
HPRD
IMGT
EMBL AC164161 AF080624
GenPept AAC29495

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca