InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: OTUD6A

Summary

InnateDB Protein

IDBP-74238.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

OTUD6A

Protein Name

OTU domain containing 6A

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000339389

InnateDB Gene

IDBG-74236 (OTUD6A)

Protein Structure

UniProt Annotation

Function

Deubiquitinating enzyme that hydrolyzes 'Lys-27'-, 'Lys- 29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. {ECO:0000269PubMed:23827681}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004843	ubiquitin-specific protease activity

Biological Process

GO:0006508	proteolysis
GO:0035523	protein K29-linked deubiquitination
GO:0035871	protein K11-linked deubiquitination
GO:1990167	protein K27-linked deubiquitination
GO:1990168	protein K33-linked deubiquitination