InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pou2f3

Summary

InnateDB Protein

IDBP-742480.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pou2f3

Protein Name

Synonyms

Epoc-1; Oct-11a; Oct11; Otf-11; Otf11; Skin; Skin-1a; Skn-1a; Skn-li;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000135115

InnateDB Gene

IDBG-155125 (Pou2f3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0046983	protein dimerization activity

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0008544	epidermis development
GO:0030216	keratinocyte differentiation
GO:0042060	wound healing
GO:0043922	negative regulation by host of viral transcription
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:102565

InterPro

IPR000327 POU-specific
IPR000972 Octamer-binding transcription factor
IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR010982 Lambda repressor-like, DNA-binding domain
IPR013847 POU domain

PFAM

PF00157
PF00046
PF13413

PRINTS

PR00029
PR00028

PIRSF

SMART

SM00352
SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt