Homo sapiens Protein: ARR3
Summary
InnateDB Protein IDBP-74320.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARR3
Protein Name arrestin 3, retinal (X-arrestin)
Synonyms ARRX;
Species Homo sapiens
Ensembl Protein ENSP00000363619
InnateDB Gene IDBG-74318 (ARR3)
Protein Structure
UniProt Annotation
Function May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins.
Subcellular Localization
Disease Associations
Tissue Specificity Inner and outer segments, and the inner plexiform regions of the retina.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 31 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007601 visual perception
Cellular Component
GO:0001917 photoreceptor inner segment
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000698 Arrestin
IPR011021 Arrestin-like, N-terminal
IPR011022 Arrestin C-terminal-like domain
IPR014756 Immunoglobulin E-set
PFAM PF00339
PF02752
PRINTS PR00309
PIRSF
SMART SM01017
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P36575
PhosphoSite PhosphoSite-
TrEMBL D6RCT3
UniProt Splice Variant
Entrez Gene 407
UniGene Hs.308
RefSeq
HUGO HGNC:710
OMIM 301770
CCDS
HPRD 02358
IMGT
EMBL AF033105 AF076497 AF076498 AF076499 AF076500 AF076501 AF076502 AF076503 AF076504 AF076505 AF076506 AF076507 AF076508 AF076509 AF076510 AF076511 AF076512 AL357752 BC012096 CR456849 EU883571 U03626
GenPept AAB84302 AAC27524 AAC78395 AAH12096 ACG60645 CAG33130 CAI41490 CAI41491