InnateDB Protein
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IDBP-74532.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PPIG
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Protein Name
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peptidylprolyl isomerase G (cyclophilin G)
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Synonyms
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CARS-Cyp; CYP; SCAF10; SRCyp;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000260970
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InnateDB Gene
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IDBG-74530 (PPIG)
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Protein Structure
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Function |
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.
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Subcellular Localization |
Nucleus matrix {ECO:0000269PubMed:15358154}. Nucleus speckle {ECO:0000269PubMed:15358154}. Note=Colocalizes with RNA splicing factors at nuclear speckles.
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Disease Associations |
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Tissue Specificity |
Ubiquitous.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
27
[view]
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Protein-Protein |
27
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002130
Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
IPR029000
Cyclophilin-like domain
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PFAM |
PF00160
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PRINTS |
PR00153
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q13427
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PhosphoSite |
PhosphoSite-Q13427
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TrEMBL |
C9JT64
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UniProt Splice Variant |
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Entrez Gene |
9360
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UniGene |
Hs.734172
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RefSeq |
NP_004783
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HUGO |
HGNC:14650
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OMIM |
606093
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CCDS |
CCDS2235
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HPRD |
12083
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IMGT |
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EMBL |
AC016772
AC093899
BC001555
CH471058
U40763
X99717
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GenPept |
AAB40347
AAH01555
AAY24119
AAY24233
CAA68053
EAX11267
EAX11268
EAX11269
EAX11270
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