Homo sapiens Protein: ISLR2
Summary
InnateDB Protein IDBP-745774.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ISLR2
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000458080
InnateDB Gene IDBG-21815 (ISLR2)
Protein Structure
UniProt Annotation
Function Required for axon extension during neural development. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0045773 positive regulation of axon extension
Cellular Component
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
PFAM PF01463
PF00560
PF13504
PF13855
PF00041
PF01108
PRINTS
PIRSF
SMART SM00082
SM00369
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6UXK2
PhosphoSite PhosphoSite-Q6UXK2
TrEMBL H3BNZ6
UniProt Splice Variant
Entrez Gene 57611
UniGene Hs.254775
RefSeq
HUGO HGNC:29286
OMIM 614179
CCDS CCDS10259
HPRD 13865
IMGT
EMBL AB040898 AC010931 AK290467 AY358316
GenPept AAQ88682 BAA95989 BAF83156