Version 5.4
Homo sapiens Protein: TRIM29
Summary
InnateDB Protein IDBP-74578.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM29
Protein Name tripartite motif containing 29
Synonyms ATDC;
Species Homo sapiens
Ensembl Protein ENSP00000343129
InnateDB Gene IDBG-74574 (TRIM29)
Protein Structure
UniProt Annotation
Function It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:7644499}. Note=Colocalizes with intermediate filaments.
Disease Associations
Tissue Specificity Expressed in placenta, prostate and thymus. {ECO:0000269PubMed:11331580}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
Experimentally validated
Total 47 [view]
Protein-Protein 47 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:1900181 negative regulation of protein localization to nucleus
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000315 Zinc finger, B-box
PFAM PF00643
PRINTS
PIRSF
SMART SM00336
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14134
PhosphoSite PhosphoSite-Q14134
TrEMBL E9PM74
UniProt Splice Variant
Entrez Gene 23650
UniGene Hs.626329
RefSeq NP_036233
HUGO HGNC:17274
OMIM 610658
CCDS CCDS8428
HPRD 10280
IMGT
EMBL AF230388 AF230389 AK299472 AP000679 AP001360 BC017352 CH471065 L24203
GenPept AAA35762 AAG50167 AAG50168 AAH17352 BAH13044 EAW67497 EAW67498

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca