Homo sapiens Protein: ADAMTSL3 | |||||||||
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Summary | |||||||||
InnateDB Protein | IDBP-745971.3 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | ADAMTSL3 | ||||||||
Protein Name | |||||||||
Synonyms | |||||||||
Species | Homo sapiens | ||||||||
Ensembl Protein | ENSP00000456313 | ||||||||
InnateDB Gene | IDBG-27283 (ADAMTSL3) | ||||||||
Protein Structure | |||||||||
UniProt Annotation | |||||||||
Function | |||||||||
Subcellular Localization | Secreted, extracellular space, extracellular matrix {ECO:0000269PubMed:14667842}. | ||||||||
Disease Associations | |||||||||
Tissue Specificity | Expressed in epithelial cells of the colon, fallopian tube, skin, breast, prostate, epididymis, liver, pancreatic islets and bile ducts, as well as by vascular endothelial cells, smooth muscle cells, fibroblasts, cortical and ganglionic neurons and cardiac myocytes. Also expressed by malignant epithelial cells in colon cancer, as well as breast, prostate, renal and skin tumors. Expression is significantly reduced in colon cancer compared to normal colon. {ECO:0000269PubMed:14667842, ECO:0000269PubMed:17597111}. | ||||||||
Comments | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||
PDB ID | |||||||||
InterPro |
IPR000884
Thrombospondin, type 1 repeat IPR003598 Immunoglobulin subtype 2 IPR003599 Immunoglobulin subtype IPR007110 Immunoglobulin-like domain IPR013098 Immunoglobulin I-set IPR013151 Immunoglobulin IPR013273 Peptidase M12B, ADAM-TS |
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PFAM |
PF00090
PF07679 PF00047 |
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PRINTS |
PR01857
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PIRSF | |||||||||
SMART |
SM00209
SM00408 SM00409 |
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TIGRFAMs | |||||||||
Post-translational Modifications | |||||||||
Modification | |||||||||
Cross-References | |||||||||
SwissProt | P82987 | ||||||||
PhosphoSite | PhosphoSite-P82987 | ||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 57188 | ||||||||
UniGene | Hs.623687 | ||||||||
RefSeq | NP_001288039 | ||||||||
HUGO | HGNC:14633 | ||||||||
OMIM | 609199 | ||||||||
CCDS | CCDS73773 | ||||||||
HPRD | 12426 | ||||||||
IMGT | |||||||||
EMBL | AB033059 AC027807 AC087738 AC116157 AF237652 BC128389 BC128390 | ||||||||
GenPept | AAI28390 AAI28391 AAK15041 BAA86547 | ||||||||