Version 5.4
Homo sapiens Protein: FUS
Summary
InnateDB Protein IDBP-746165.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FUS
Protein Name
Synonyms ALS6; ETM4; FUS1; HNRNPP2; POMP75; TLS;
Species Homo sapiens
Ensembl Protein ENSP00000455282
InnateDB Gene IDBG-27917 (FUS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 319 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 319 [view]
Protein-Protein 318 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR001876 Zinc finger, RanBP2-type
PFAM PF00076
PF00641
PRINTS
PIRSF
SMART SM00360
SM00547
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H3BPE7
UniProt Splice Variant
Entrez Gene 2521
UniGene Hs.724154
RefSeq
HUGO HGNC:4010
OMIM 137070
CCDS
HPRD 00660
IMGT
EMBL AC009088
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca