InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CSTF2T

Summary

InnateDB Protein

IDBP-74663.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CSTF2T

Protein Name

cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant

Synonyms

CstF-64T;

Species

Homo sapiens

Ensembl Protein

ENSP00000332444

InnateDB Gene

IDBG-74661 (CSTF2T)

Protein Structure

UniProt Annotation

Function

May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.

Experimentally validated
Total	9 [view]
Protein-Protein	8 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006397

mRNA processing

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000504 RNA recognition motif domain

PFAM

PF00076

PRINTS

PIRSF

SMART

SM00360

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9H0L4

PhosphoSite

PhosphoSite-Q9H0L4

TrEMBL

UniProt Splice Variant

Entrez Gene

23283

UniGene

Hs.674231

RefSeq

NP_056050

HUGO

HGNC:17086

OMIM

611968

CCDS

CCDS7245

HPRD

09900

IMGT

EMBL

AB014589 AK222574 AK314318 AL136747 AY130299 BC028239 CH471083

GenPept

AAH28239 AAN05429 BAA31664 BAD96294 BAG36966 CAB66681 EAW54142