Version 5.4
Homo sapiens Protein: CYP1A1
Summary
InnateDB Protein IDBP-746835.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CYP1A1
Protein Name
Synonyms AHH; AHRR; CP11; CYP1; P1-450; P450-C; P450DX;
Species Homo sapiens
Ensembl Protein ENSP00000457668
InnateDB Gene IDBG-22475 (CYP1A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0070330 aromatase activity
GO:0070576 vitamin D 24-hydroxylase activity
Biological Process
GO:0006805 xenobiotic metabolic process
GO:0017144 drug metabolic process
GO:0019369 arachidonic acid metabolic process
GO:0019373 epoxygenase P450 pathway
GO:0042359 vitamin D metabolic process
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
GO:0071407 cellular response to organic cyclic compound
GO:0097267 omega-hydroxylase P450 pathway
Cellular Component
GO:0005789 endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID
InterPro IPR001128 Cytochrome P450
IPR002401 Cytochrome P450, E-class, group I
IPR008066 Cytochrome P450, E-class, group I, CYP1
PFAM PF00067
PRINTS PR00385
PR00463
PR01683
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P04798
PhosphoSite PhosphoSite-P04798
TrEMBL
UniProt Splice Variant
Entrez Gene 1543
UniGene Hs.739773
RefSeq
HUGO HGNC:2595
OMIM 108330
CCDS
HPRD 00148
IMGT
EMBL AC091230 AF040259 AF253322 AK223113 AM233518 AM233519 AM233520 BC023019 K03191 M12079 X02612 X04300
GenPept AAA52139 AAA52152 AAD10199 AAH23019 AAK25727 BAD96833 CAA26458 CAA27843 CAJ80721 CAJ80722 CAJ80723

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca