InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RAB11A

Summary

InnateDB Protein

IDBP-747330.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAB11A

Protein Name

Synonyms

YL8;

Species

Homo sapiens

Ensembl Protein

ENSP00000456420

InnateDB Gene

IDBG-17737 (RAB11A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 69 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	69 [view]
Protein-Protein	65 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019905	syntaxin binding

Biological Process

GO:0000910	cytokinesis
GO:0006184	GTP catabolic process
GO:0006833	water transport
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0031175	neuron projection development
GO:0032402	melanosome transport
GO:0045087	innate immune response (InnateDB)
GO:0048227	plasma membrane to endosome transport
GO:0055085	transmembrane transport
GO:0072659	protein localization to plasma membrane

Cellular Component

GO:0005622	intracellular
GO:0005802	trans-Golgi network
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0030659	cytoplasmic vesicle membrane
GO:0030670	phagocytic vesicle membrane
GO:0032154	cleavage furrow
GO:0043234	protein complex
GO:0045335	phagocytic vesicle
GO:0055037	recycling endosome
GO:0055038	recycling endosome membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000795 Elongation factor, GTP-binding domain
IPR001806 Small GTPase superfamily
IPR003578 Small GTPase superfamily, Rho type
IPR003579 Small GTPase superfamily, Rab type
IPR005225 Small GTP-binding protein domain
IPR006689 Small GTPase superfamily, ARF/SAR type
IPR013684 Mitochondrial Rho-like
IPR020849 Small GTPase superfamily, Ras type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00009
PF00071
PF00025
PF08477

PRINTS

PR00315
PR00449
PR00328

PIRSF

SMART

SM00174
SM00175
SM00173

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt