Version 5.4
Homo sapiens Protein: ZCCHC6
Summary
InnateDB Protein IDBP-74750.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZCCHC6
Protein Name zinc finger, CCHC domain containing 6
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000365124
InnateDB Gene IDBG-74738 (ZCCHC6)
Protein Structure
UniProt Annotation
Function Uridylyltransferase that mediates the terminal uridylation of some specific RNAs. Not involved in uridylation of precursor let-7 (pre-let-7) miRNA. Does not play a role in replication-dependent histone mRNA degradation. {ECO:0000269PubMed:19703396}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
GO:0050265 RNA uridylyltransferase activity
Biological Process
GO:0031123 RNA 3'-end processing
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001878 Zinc finger, CCHC-type
IPR002058 PAP/25A-associated
PFAM PF00098
PF03828
PRINTS
PIRSF
SMART SM00343
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5VYS8
PhosphoSite PhosphoSite-Q5VYS8
TrEMBL
UniProt Splice Variant
Entrez Gene 79670
UniGene Hs.653413
RefSeq
HUGO HGNC:25817
OMIM
CCDS
HPRD 11697
IMGT
EMBL AB051498 AK023471 AK055546 AK055948 AL137849 AL353678 AL832026 AL832193 BC032456 BX641077 CR933643 CR933644 CR936608
GenPept AAH32456 BAB14584 BAB21802 BAB70951 BAB71052 CAE46038 CAH56214 CAH56219 CAH71514 CAH71515 CAH71518 CAH71519 CAI14918 CAI14919 CAI14920 CAI14921 CAI45944 CAI45945 CAI56753

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca