Version 5.4
Homo sapiens Protein: NEIL1
Summary
InnateDB Protein IDBP-747584.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEIL1
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000456852
InnateDB Gene IDBG-23214 (NEIL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003684 damaged DNA binding
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity
GO:0008270 zinc ion binding
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
Biological Process
GO:0000737 DNA catabolic process, endonucleolytic
GO:0006284 base-excision repair
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR012319 DNA glycosylase/AP lyase, catalytic domain
PFAM PF01149
PRINTS
PIRSF
SMART SM00898
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H3BU98
UniProt Splice Variant
Entrez Gene 79661
UniGene Hs.512732
RefSeq
HUGO HGNC:18448
OMIM 608844
CCDS
HPRD 12314
IMGT
EMBL AC068338
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca