InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC32A1

Summary

InnateDB Protein

IDBP-74859.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC32A1

Protein Name

solute carrier family 32 (GABA vesicular transporter), member 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000217420

InnateDB Gene

IDBG-74857 (SLC32A1)

Protein Structure

UniProt Annotation

Function

Involved in the uptake of GABA and glycine into the synaptic vesicles.

Subcellular Localization

Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Retina. Expressed throughout the horizontal cells or more specifically at the terminals. {ECO:0000269PubMed:12115694}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015187	glycine transmembrane transporter activity
GO:0015495	gamma-aminobutyric acid:hydrogen symporter activity

Biological Process

GO:0006811	ion transport
GO:0007268	synaptic transmission
GO:0007269	neurotransmitter secretion
GO:0007568	aging
GO:0015812	gamma-aminobutyric acid transport
GO:0015816	glycine transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0008021	synaptic vesicle
GO:0016021	integral component of membrane
GO:0030425	dendrite
GO:0030672	synaptic vesicle membrane
GO:0043005	neuron projection
GO:0043229	intracellular organelle
GO:0044292	dendrite terminus
GO:0044306	neuron projection terminus
GO:0044316	cone cell pedicle
GO:0045202	synapse
GO:0051286	cell tip
GO:0060077	inhibitory synapse
GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane