Version 5.4
Homo sapiens Protein: NUTF2
Summary
InnateDB Protein IDBP-749333.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUTF2
Protein Name
Synonyms NTF2; PP15;
Species Homo sapiens
Ensembl Protein ENSP00000457022
InnateDB Gene IDBG-37425 (NUTF2)
Protein Structure
UniProt Annotation
Function Facilitates protein transport into the nucleus. Interacts with the nucleoporin p62 and with Ran. Acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 15 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
Biological Process
GO:0006611 protein export from nucleus
GO:0006810 transport
Cellular Component
GO:0005622 intracellular
GO:0005643 nuclear pore
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002075 Nuclear transport factor 2
IPR018222 Nuclear transport factor 2, eukaryote
PFAM PF02136
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P61970
PhosphoSite PhosphoSite-P61970
TrEMBL H3BRV9
UniProt Splice Variant
Entrez Gene 128322
UniGene Hs.741356
RefSeq XP_003960157
HUGO HGNC:13722
OMIM 605813
CCDS CCDS10848
HPRD 12050
IMGT
EMBL AC040162 AK311822 BC002348 CH471092 CR456937 U43939 X07315
GenPept AAA85905 AAH02348 BAG34764 CAA30278 CAG33218 EAW83181 EAW83182

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca