Version 5.4
Homo sapiens Protein: SLC38A7
Summary
InnateDB Protein IDBP-749395.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC38A7
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000454646
InnateDB Gene IDBG-34673 (SLC38A7)
Protein Structure
UniProt Annotation
Function Mediates sodium-dependent transport of amino acids, preferentially L-glutamine. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=In neurons, located in soma and axons. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005290 L-histidine transmembrane transporter activity
GO:0005313 L-glutamate transmembrane transporter activity
GO:0015179 L-amino acid transmembrane transporter activity
GO:0015180 L-alanine transmembrane transporter activity
GO:0015182 L-asparagine transmembrane transporter activity
GO:0015183 L-aspartate transmembrane transporter activity
GO:0015186 L-glutamine transmembrane transporter activity
GO:0015190 L-leucine transmembrane transporter activity
GO:0015191 L-methionine transmembrane transporter activity
GO:0015194 L-serine transmembrane transporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006814 sodium ion transport
GO:0006867 asparagine transport
GO:0006868 glutamine transport
GO:0015803 branched-chain amino acid transport
GO:0015804 neutral amino acid transport
GO:0015807 L-amino acid transport
GO:0015808 L-alanine transport
GO:0015810 aspartate transport
GO:0015813 L-glutamate transport
GO:0015817 histidine transport
GO:0015821 methionine transport
GO:0015825 L-serine transport
GO:1902475 L-alpha-amino acid transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
GO:0030424 axon
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID
InterPro IPR013057 Amino acid transporter, transmembrane
IPR018227 Tryptophan/tyrosine permease
PFAM PF01490
PF03222
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NVC3
PhosphoSite PhosphoSite-Q9NVC3
TrEMBL H3BRZ0
UniProt Splice Variant
Entrez Gene 55238
UniGene Hs.10499
RefSeq
HUGO HGNC:25582
OMIM 614236
CCDS CCDS10800
HPRD 07701
IMGT
EMBL AC010287 AK001677 AK022786 AK222932 BC001961 CH471092 CR457236
GenPept AAH01961 BAA91830 BAB14244 BAD96652 CAG33517 EAW82985

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca