Version 5.4
Homo sapiens Protein: CX3CL1
Summary
InnateDB Protein IDBP-750758.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CX3CL1
Protein Name
Synonyms ABCD-3; C3Xkine; CXC3; CXC3C; fractalkine; neurotactin; NTN; NTT; SCYD1;
Species Homo sapiens
Ensembl Protein ENSP00000464114
InnateDB Gene IDBG-33205 (CX3CL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008009 chemokine activity
Biological Process
GO:0006955 immune response
Cellular Component
GO:0005576 extracellular region
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001811 Chemokine interleukin-8-like domain
IPR008097 CX3C chemokine ligand 1
PFAM PF00048
PRINTS PR01721
PIRSF
SMART SM00199
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL J3QRA1
UniProt Splice Variant
Entrez Gene 6376
UniGene Hs.531668
RefSeq
HUGO HGNC:10647
OMIM 601880
CCDS
HPRD 03529
IMGT
EMBL AC009052
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca