Version 5.4
Homo sapiens Protein: CKS2
Summary
InnateDB Protein IDBP-75308.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CKS2
Protein Name CDC28 protein kinase regulatory subunit 2
Synonyms CKSHS2;
Species Homo sapiens
Ensembl Protein ENSP00000364976
InnateDB Gene IDBG-75306 (CKS2)
Protein Structure
UniProt Annotation
Function Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
Experimentally validated
Total 32 [view]
Protein-Protein 26 [view]
Protein-DNA 6 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0007049 cell cycle
GO:0007051 spindle organization
GO:0007127 meiosis I
GO:0008283 cell proliferation
GO:0048015 phosphatidylinositol-mediated signaling
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000789 Cyclin-dependent kinase, regulatory subunit
PFAM PF01111
PRINTS PR00296
PIRSF
SMART SM01084
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P33552
PhosphoSite PhosphoSite-P33552
TrEMBL
UniProt Splice Variant
Entrez Gene 1164
UniGene
RefSeq NP_001818
HUGO HGNC:2000
OMIM 116901
CCDS CCDS6682
HPRD 00300
IMGT
EMBL AF506708 AL160054 BC006458 BT006630 CH471089 CR407630 CR542118 X54942
GenPept AAH06458 AAM22232 AAP35276 CAA38703 CAG28558 CAG46915 CAI41365 EAW62762

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca