InnateDB Protein
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IDBP-75326.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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OLA1
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Protein Name
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Obg-like ATPase 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000340167
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InnateDB Gene
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IDBG-75322 (OLA1)
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Protein Structure
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Function |
Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
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Subcellular Localization |
Cytoplasm {ECO:0000255HAMAP-Rule:MF_03167, ECO:0000269PubMed:20053727}. Nucleus {ECO:0000255HAMAP- Rule:MF_03167, ECO:0000269PubMed:20053727}. Nucleus, nucleolus {ECO:0000255HAMAP-Rule:MF_03167, ECO:0000269PubMed:20053727}. Note=Predominantly cytoplasmic, shuttles between the nucleus and the cytoplasm.
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Disease Associations |
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Tissue Specificity |
Expressed in all tissues tested but its expression is more abundant in testis, liver, lung, and brain. Overexpressed in several malignancies, including cancers of the colon, rectum, ovary, lung, stomach, and uterus.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
38
[view]
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Protein-Protein |
38
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR012676
TGS-like
IPR013029
Domain of unknown function DUF933
IPR027417
P-loop containing nucleoside triphosphate hydrolase
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PFAM |
PF06071
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NTK5
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PhosphoSite |
PhosphoSite-Q9NTK5
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TrEMBL |
Q53SQ6
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UniProt Splice Variant |
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Entrez Gene |
29789
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UniGene |
Hs.712643
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RefSeq |
NP_001011708
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HUGO |
HGNC:28833
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OMIM |
611175
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CCDS |
CCDS42779
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HPRD |
15194
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IMGT |
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EMBL |
AC013467
AC016737
AF078859
AF078868
AF116703
AF134478
AK027523
AK074710
AL136546
BC012842
BC013925
BC029376
BC091522
CH471058
DQ250006
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GenPept |
AAD44491
AAD44500
AAF71123
AAH12842
AAH13925
AAH29376
AAH91522
AAP97255
AAY14876
ABB72766
BAB55174
BAC11153
CAB66481
EAX11151
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