InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LPIN3

Summary

InnateDB Protein

IDBP-75376.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LPIN3

Protein Name

lipin 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000362354

InnateDB Gene

IDBG-75372 (LPIN3)

Protein Structure

UniProt Annotation

Function

Regulates fatty acid metabolism. Magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Significant expression in intestine and other regions of the gastrointestinal tract. {ECO:0000269PubMed:17158099}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008195	phosphatidate phosphatase activity

Biological Process

GO:0006631	fatty acid metabolic process
GO:0006644	phospholipid metabolic process
GO:0006646	phosphatidylethanolamine biosynthetic process
GO:0006656	phosphatidylcholine biosynthetic process
GO:0016311	dephosphorylation
GO:0044281	small molecule metabolic process
GO:0046474	glycerophospholipid biosynthetic process