InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RHOBTB1

Summary

InnateDB Protein

IDBP-75409.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RHOBTB1

Protein Name

Rho-related BTB domain containing 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000350595

InnateDB Gene

IDBG-75407 (RHOBTB1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues. {ECO:0000269PubMed:12426103}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0051056	regulation of small GTPase mediated signal transduction

Cellular Component

GO:0005622	intracellular
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000210 BTB/POZ-like
IPR001806 Small GTPase superfamily
IPR003578 Small GTPase superfamily, Rho type
IPR003579 Small GTPase superfamily, Rab type
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
IPR013684 Mitochondrial Rho-like
IPR020849 Small GTPase superfamily, Ras type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00071
PF00651
PF08477

PRINTS

PR00449

PIRSF

SMART

SM00225
SM00174
SM00175
SM00173

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt