Version 5.4
Homo sapiens Protein: REEP3
Summary
InnateDB Protein IDBP-75683.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol REEP3
Protein Name receptor accessory protein 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000298249
InnateDB Gene IDBG-75681 (REEP3)
Protein Structure
UniProt Annotation
Function Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes. {ECO:0000269PubMed:23911198}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Protein Structure and Domains
PDB ID
InterPro IPR004345 TB2/DP1/HVA22-related protein
PFAM PF03134
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q6NUK4
TrEMBL X6R3X1
UniProt Splice Variant
Entrez Gene 221035
UniGene Hs.614003
RefSeq XP_005269677
HUGO HGNC:23711
OMIM 609348
CCDS
HPRD 16582
IMGT
EMBL AC022022 AC022387 AL607062
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca