Version 5.4
Homo sapiens Protein: SPATA22
Summary
InnateDB Protein IDBP-757814.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPATA22
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000459580
InnateDB Gene IDBG-17003 (SPATA22)
Protein Structure
UniProt Annotation
Function Meiosis-specific protein required for homologous recombination in meiosis I. {ECO:0000250}.
Subcellular Localization Chromosome {ECO:0000250}. Note=Localizes on meiotic chromosome axes. Accumulates on resected DNA. Localization is dependent on MEIOB (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in adult testis. {ECO:0000269PubMed:15713825}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000711 meiotic DNA repair synthesis
GO:0007129 synapsis
GO:0007276 gamete generation
GO:0009566 fertilization
GO:0051445 regulation of meiotic cell cycle
GO:0061458 reproductive system development
Cellular Component
GO:0005694 chromosome
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NHS9
PhosphoSite PhosphoSite-Q8NHS9
TrEMBL I3L517
UniProt Splice Variant
Entrez Gene 84690
UniGene Hs.351068
RefSeq XP_005256885
HUGO HGNC:30705
OMIM
CCDS CCDS11027
HPRD 14862
IMGT
EMBL AC025125 AF367472 AK301892 AY032684 AY035867 AY035868 BC029483 CH471108
GenPept AAH29483 AAK51120 AAK53408 AAK61373 AAK61374 BAG63323 EAW90508 EAW90509 EAW90510 EAW90511

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca