Version 5.4
Homo sapiens Protein: HIC1
Summary
InnateDB Protein IDBP-758293.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HIC1
Protein Name
Synonyms hic-1; ZBTB29; ZNF901;
Species Homo sapiens
Ensembl Protein ENSP00000460268
InnateDB Gene IDBG-16011 (HIC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 45 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 45 [view]
Protein-Protein 44 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
PFAM PF00651
PRINTS
PIRSF
SMART SM00225
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL V9GYA4
UniProt Splice Variant
Entrez Gene 3090
UniGene Hs.72956
RefSeq
HUGO HGNC:4909
OMIM 603825
CCDS
HPRD 04826
IMGT
EMBL AC090617
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca